EFFECTS OF THALAMIC STROKE ON ENERGY METABOLISM OF THE CEREBRAL CORTEX
Identifieur interne : 001A20 ( Main/Exploration ); précédent : 001A19; suivant : 001A21EFFECTS OF THALAMIC STROKE ON ENERGY METABOLISM OF THE CEREBRAL CORTEX
Auteurs : J. C. Baron [France] ; R. D'Antona ; P. Pantano ; M. Serdaru [France] ; Y. Samson ; M. G. Bousser [France]Source :
- Brain [ 0006-8950 ] ; 1986-12.
Abstract
Positron emission tomography was used to study the effects of unilateral vascular thalamic lesions on cortical oxygen and glucose utilization in 10 patients. There was significant ipsilateral cortex hypometabolism in 9 of the 10 patients, affecting the whole cortical mantle diffusely. The only patient spared was free of neuropsychological deficit at the time of positron emission tomography. In 4 patients, the magnitude of ipsilateral cortical hypometabolism was significantly less at a follow-up PET study, when neuropsychological function had improved When taken together, the 14 studies showed a significant tendency for the hypometabolism to improve with taken together, the 14 studies showed a significant tendency for the hypometabolism to improve with time after clinical onset. These data suggest that the ipsilateral cortical hypometabolism results from damage to the thalamo-cortical connections and reflect either loss of nonspecific activating afferences or a degenerative deafferentation-deefferentation process, or both. Its links with the concept of diaschisis are suggested by its tendency to recover. A causal relationship between cortical hypometabolism and neuropsychological deficit, however, although strongly suggested, cannot be firmly established from the present data.
Url:
DOI: 10.1093/brain/109.6.1243
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000F31
- to stream Istex, to step Curation: 000F31
- to stream Istex, to step Checkpoint: 001519
- to stream Main, to step Merge: 001B28
- to stream Main, to step Curation: 001A20
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>EFFECTS OF THALAMIC STROKE ON ENERGY METABOLISM OF THE CEREBRAL CORTEX</title><author><name sortKey="Baron, J C" sort="Baron, J C" uniqKey="Baron J" first="J. C." last="Baron">J. C. Baron</name></author><author><name sortKey="D Antona, R" sort="D Antona, R" uniqKey="D Antona R" first="R." last="D'Antona">R. D'Antona</name></author><author><name sortKey="Pantano, P" sort="Pantano, P" uniqKey="Pantano P" first="P." last="Pantano">P. Pantano</name></author><author><name sortKey="Serdaru, M" sort="Serdaru, M" uniqKey="Serdaru M" first="M." last="Serdaru">M. Serdaru</name></author><author><name sortKey="Samson, Y" sort="Samson, Y" uniqKey="Samson Y" first="Y." last="Samson">Y. Samson</name></author><author><name sortKey="Bousser, M G" sort="Bousser, M G" uniqKey="Bousser M" first="M. G." last="Bousser">M. G. Bousser</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6CDAAE6AC69AB067D4B8549D1614D144292D3DCB</idno><date when="1986" year="1986">1986</date><idno type="doi">10.1093/brain/109.6.1243</idno><idno type="url">https://api.istex.fr/document/6CDAAE6AC69AB067D4B8549D1614D144292D3DCB/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000F31</idno><idno type="wicri:Area/Istex/Curation">000F31</idno><idno type="wicri:Area/Istex/Checkpoint">001519</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001519</idno><idno type="wicri:doubleKey">0006-8950:1986:Baron J:effects:of:thalamic</idno><idno type="wicri:Area/Main/Merge">001B28</idno><idno type="wicri:Area/Main/Curation">001A20</idno><idno type="wicri:Area/Main/Exploration">001A20</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">EFFECTS OF THALAMIC STROKE ON ENERGY METABOLISM OF THE CEREBRAL CORTEX</title><author><name sortKey="Baron, J C" sort="Baron, J C" uniqKey="Baron J" first="J. C." last="Baron">J. C. Baron</name><affiliation></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Cliniques des Maladies du Systeme Nerveux Paris</wicri:regionArea></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Correspondence to Dr J. C Baron, Service Hospitalier Frederic Joliot, Hopital d'Orsay, 91406 Orsay</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Orsay</settlement></placeName></affiliation></author><author><name sortKey="D Antona, R" sort="D Antona, R" uniqKey="D Antona R" first="R." last="D'Antona">R. D'Antona</name><affiliation><wicri:noCountry code="subField">Orsay</wicri:noCountry></affiliation></author><author><name sortKey="Pantano, P" sort="Pantano, P" uniqKey="Pantano P" first="P." last="Pantano">P. Pantano</name><affiliation><wicri:noCountry code="subField">Orsay</wicri:noCountry></affiliation></author><author><name sortKey="Serdaru, M" sort="Serdaru, M" uniqKey="Serdaru M" first="M." last="Serdaru">M. Serdaru</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Neurologie et de Neuropsychologie, La Salpetriere Paris</wicri:regionArea><wicri:noRegion>La Salpetriere Paris</wicri:noRegion><wicri:noRegion>La Salpetriere Paris</wicri:noRegion></affiliation></author><author><name sortKey="Samson, Y" sort="Samson, Y" uniqKey="Samson Y" first="Y." last="Samson">Y. Samson</name><affiliation><wicri:noCountry code="subField">Orsay</wicri:noCountry></affiliation></author><author><name sortKey="Bousser, M G" sort="Bousser, M G" uniqKey="Bousser M" first="M. G." last="Bousser">M. G. Bousser</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Cliniques des Maladies du Systeme Nerveux Paris</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Brain</title><idno type="ISSN">0006-8950</idno><idno type="eISSN">1460-2156</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="1986-12">1986-12</date><biblScope unit="volume">109</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="1243">1243</biblScope><biblScope unit="page" to="1259">1259</biblScope></imprint><idno type="ISSN">0006-8950</idno></series><idno type="istex">6CDAAE6AC69AB067D4B8549D1614D144292D3DCB</idno><idno type="DOI">10.1093/brain/109.6.1243</idno><idno type="ArticleID">109.6.1243</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0006-8950</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Positron emission tomography was used to study the effects of unilateral vascular thalamic lesions on cortical oxygen and glucose utilization in 10 patients. There was significant ipsilateral cortex hypometabolism in 9 of the 10 patients, affecting the whole cortical mantle diffusely. The only patient spared was free of neuropsychological deficit at the time of positron emission tomography. In 4 patients, the magnitude of ipsilateral cortical hypometabolism was significantly less at a follow-up PET study, when neuropsychological function had improved When taken together, the 14 studies showed a significant tendency for the hypometabolism to improve with taken together, the 14 studies showed a significant tendency for the hypometabolism to improve with time after clinical onset. These data suggest that the ipsilateral cortical hypometabolism results from damage to the thalamo-cortical connections and reflect either loss of nonspecific activating afferences or a degenerative deafferentation-deefferentation process, or both. Its links with the concept of diaschisis are suggested by its tendency to recover. A causal relationship between cortical hypometabolism and neuropsychological deficit, however, although strongly suggested, cannot be firmly established from the present data.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Orsay</li></settlement></list><tree><noCountry><name sortKey="D Antona, R" sort="D Antona, R" uniqKey="D Antona R" first="R." last="D'Antona">R. D'Antona</name><name sortKey="Pantano, P" sort="Pantano, P" uniqKey="Pantano P" first="P." last="Pantano">P. Pantano</name><name sortKey="Samson, Y" sort="Samson, Y" uniqKey="Samson Y" first="Y." last="Samson">Y. Samson</name></noCountry><country name="France"><noRegion><name sortKey="Baron, J C" sort="Baron, J C" uniqKey="Baron J" first="J. C." last="Baron">J. C. Baron</name></noRegion><name sortKey="Baron, J C" sort="Baron, J C" uniqKey="Baron J" first="J. C." last="Baron">J. C. Baron</name><name sortKey="Bousser, M G" sort="Bousser, M G" uniqKey="Bousser M" first="M. G." last="Bousser">M. G. Bousser</name><name sortKey="Serdaru, M" sort="Serdaru, M" uniqKey="Serdaru M" first="M." last="Serdaru">M. Serdaru</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Eau/explor/LotaV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A20 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001A20 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Eau
|area= LotaV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:6CDAAE6AC69AB067D4B8549D1614D144292D3DCB
|texte= EFFECTS OF THALAMIC STROKE ON ENERGY METABOLISM OF THE CEREBRAL CORTEX
}}
| This area was generated with Dilib version V0.6.39. |  |